Aging, Longevity and Health in the News


Nature: Current issue

Cancer patients need better care, not just more technology
by Richard SullivanC. S. PrameshChristopher M. Booth
19 Sep 2017 at 12:00am
Treating cancer with the latest drugs and techniques is costly and will not improve survival globally, warn Richard Sullivan, C. S. Pramesh and Christopher M. Booth.
Cell signalling: Red alert about lipid's role in skin cancer
by Ian J. JacksonE. Elizabeth Patton
6 Sep 2017 at 12:00am
Some versions of the MC1R protein are associated with red hair and an increased risk of developing a skin cancer called melanoma. It emerges that a lipid that binds MC1R might provide a target to reduce this risk. See Letter p.399
Metallurgy: No more tears for metal 3D printing
by Iain Todd
20 Sep 2017 at 12:00am
3D printing could revolutionize manufacturing processes involving metals, but few industrially useful alloys are compatible with the technique. A method has been developed that might open up the 3D printing of all metals. See Letter p.365
Cell biology: The persistence of memory
by Katarzyna M. KedzioraJeremy E. Purvis
6 Sep 2017 at 12:00am
Live imaging reveals that whether or not a daughter cell proliferates is influenced by two molecular factors inherited from its mother, providing insight into how the behaviour of a newly born cell can be predetermined. See Letter p.404
A binary main-belt comet
by Jessica AgarwalDavid JewittMax MutchlerHarold WeaverStephen Larson
20 Sep 2017 at 12:00am
Asteroids are primitive Solar System bodies that evolve both collisionally and through disruptions arising from rapid rotation. These processes can lead to the formation of binary asteroids and to the release of dust, both directly and, in some cases, through uncovering frozen volatiles. In a subset...
Metallic molybdenum disulfide nanosheet-based electrochemical actuators
by Muharrem AcerceE. Koray Akdo?anManish Chhowalla
30 Aug 2017 at 12:00am
Actuators that convert electrical energy to mechanical energy are useful in a wide variety of electromechanical systems and in robotics, with applications such as steerable catheters, adaptive wings for aircraft and drag-reducing wind turbines. Actuation systems can be based on various stimuli, such...
Palmitoylation-dependent activation of MC1R prevents melanomagenesis
by Shuyang ChenBo ZhuChengqian YinWei LiuChangpeng HanBaoen ChenTongzheng LiuXin LiXiang ChenChunying LiLimin HuJun ZhouZhi-Xiang XuXiumei GaoXu WuColin R. GodingRutao Cui
6 Sep 2017 at 12:00am
The melanocortin-1 receptor (MC1R), a G-protein-coupled receptor, has a crucial role in human and mouse pigmentation. Activation of MC1R in melanocytes by ?-melanocyte-stimulating hormone (?-MSH) stimulates cAMP signalling and melanin production and enhances DNA repair after ultraviolet irradiation....
Competing memories of mitogen and p53 signalling control cell-cycle entry
by Hee Won YangMingyu ChungTakamasa KudoTobias Meyer
6 Sep 2017 at 12:00am
Regulation of cell proliferation is necessary for immune responses, tissue repair, and upkeep of organ function to maintain human health. When proliferating cells complete mitosis, a fraction of newly born daughter cells immediately enter the next cell cycle, while the remaining cells in the same po...
The cryo-electron microscopy structure of human transcription factor IIH
by Basil J. GreberThi Hoang Duong NguyenJie FangPavel V. AfoninePaul D. AdamsEva Nogales
13 Sep 2017 at 12:00am
Human transcription factor IIH (TFIIH) is part of the general transcriptional machinery required by RNA polymerase II for the initiation of eukaryotic gene transcription. Composed of ten subunits that add up to a molecular mass of about 500?kDa, TFIIH is also essential for nucleotide excision repair...

Scientific American: Current issue

Change of Heartbeat
by Leslie Nemo
15 Aug 2017 at 12:00am
Wireless pacemakers avoid some of the risks traditional devices pose
Promiscuous Men, Chaste Women and Other Gender Myths
by Cordelia FineMark A. Elgar
15 Aug 2017 at 12:00am
The notion that behavioral differences between the sexes are innate and immutable does not hold up under scrutiny

Proceedings of the National Academy of Sciences

In This Issue [This Week in PNAS]
19 Sep 2017 at 12:06pm
Human mobility in early Europe Burial of a nonlocal female in the Lech River valley area of southern Germany. Image courtesy of Stadtarchäologie Augsburg, Augsburg, Germany. Human mobility, which includes large-scale population replacements, during the Neolithic?Bronze Age transition in central Euro...
Rome’s urban history inferred from Pb-contaminated waters trapped in i...
by Hugo Delile, Duncan Keenan–Jones, Janne Blichert–Toft, Jean–Philippe Goiran, Florent Arnaud–Godet, Francis Albarede
19 Sep 2017 at 12:06pm
Heavy metals from urban runoff preserved in sedimentary deposits record long-term economic and industrial development via the expansion and contraction of a city?s infrastructure. Lead concentrations and isotopic compositions measured in the sediments of the harbor of Ostia?Rome?s first harbor?show ...
Detection of immune responses after immunotherapy in glioblastoma using PET a...
by Joseph P. Antonios, Horacio Soto, Richard G. Everson, Diana L. Moughon, Anthony C. Wang, Joey Orpilla, Caius Radu, Benjamin M. Ellingson, Jason T. Lee, Timothy Cloughesy, Michael E. Phelps, Johannes Czernin, Linda M. Liau, Robert M. Prins
19 Sep 2017 at 12:06pm
Contrast-enhanced MRI is typically used to follow treatment response and progression in patients with glioblastoma (GBM). However, differentiating tumor progression from pseudoprogression remains a clinical dilemma largely unmitigated by current advances in imaging techniques. Noninvasive imaging te...
Dorsolateral prefrontal cortex GABA deficit in older adults with sleep-disord...
by Ana C. Pereira, Xiangling Mao, Caroline S. Jiang, Guoxin Kang, Sara Milrad, Bruce S. McEwen, Ana C. Krieger, Dikoma C. Shungu
19 Sep 2017 at 12:06pm
Sleep-disordered breathing (SDB) is a common disorder in aging that is associated with cognitive decline, including significant executive dysfunction, for which the neurobiological underpinnings remain poorly understood. Using proton magnetic resonance spectroscopy (1H MRS), this study assessed whet...
Temporal binding function of dorsal CA1 is critical for declarative memory fo...
by Azza Sellami, Alice Shaam Al Abed, Laurent Brayda–Bruno, Nicole Etchamendy, Stephane Valerio, Marie Oule, Laura Pantaleon, Valerie Lamothe, Mylene Potier, Katy Bernard, Maritza Jabourian, Cyril Herry, Nicole Mons, Pier–Vincenzo Piazza, Howard Eichenbaum, Aline Marighetto
19 Sep 2017 at 12:06pm
Temporal binding, the process that enables association between discontiguous stimuli in memory, and relational organization, a process that enables the flexibility of declarative memories, are both hippocampus-dependent and decline in aging. However, how these two processes are related in supporting...
Belief in free will affects causal attributions when ȷudging others&#x...
by Oliver Genschow, Davide Rigoni, Marcel Brass
19 Sep 2017 at 12:06pm
Free will is a cornerstone of our society, and psychological research demonstrates that questioning its existence impacts social behavior. In six studies, we tested whether believing in free will is related to the correspondence bias, which reflects people?s automatic tendency to overestimate the in...

Science

[Research Articles] Endothelial APLNR regulates tissue fatty acid uptake and ...
by Hwangbo, C., Wu, J., Papangeli, I., Adachi, T., Sharma, B., Park, S., Zhao, L., Ju, H., Go, G.-w., Cui, G., Inayathullah, M., Job, J. K., Rajadas, J., Kwei, S. L., Li, M. O., Morrison, A. R., Quertermous, T., Mani, A., Red-Horse, K., Chun, H. J.
13 Sep 2017 at 2:06pm

Treatment of type 2 diabetes mellitus continues to pose an important clinical challenge, with most existing therapies lacking demonstrable ability to improve cardiovascular outcomes. The atheroprotective peptide apelin (APLN) enhances glucose utilization and improves insulin sensitivity. However, th...


[Editors' Choice] In the mood for food
by Dzirasa, K.
13 Sep 2017 at 2:06pm

A neuronal subpopulation in the central amygdala promotes food consumption.


[Editors' Choice] Queuing up for resistance testing
by Dupnik, K.
6 Sep 2017 at 1:50pm

Antibiotic resistance in Escherichia coli can be assessed by real-time imaging of bacterial replication in a microfluidics system.


[Editors' Choice] ILCregs: The new kid in class
by Scharschmidt, T. C.
6 Sep 2017 at 1:50pm

ILCregs are a population of innate lymphoid cells that control innate intestinal inflammation through IL-10.


[Research Articles] Rare autosomal trisomies, revealed by maternal plasma DNA...
by Pertile, M. D., Halks-Miller, M., Flowers, N., Barbacioru, C., Kinnings, S. L., Vavrek, D., Seltzer, W. K., Bianchi, D. W.
30 Aug 2017 at 1:48pm

Whole-genome sequencing (WGS) of maternal plasma cell-free DNA (cfDNA) can potentially evaluate all 24 chromosomes to identify abnormalities of the placenta, fetus, or pregnant woman. Current bioinformatics algorithms typically only report on chromosomes 21, 18, 13, X, and Y; sequencing results from...


[Editors' Choice] More excitation for Rett syndrome
by Novarino, G.
30 Aug 2017 at 1:48pm

D-cycloserine ameliorates breathing abnormalities and survival rate in a mouse model of Rett syndrome.


[Research Articles] Inflammatory monocytes expressing tissue factor drive SIV...
by Schechter, M. E., Andrade, B. B., He, T., Richter, G. H., Tosh, K. W., Policicchio, B. B., Singh, A., Raehtz, K. D., Sheikh, V., Ma, D., Brocca-Cofano, E., Apetrei, C., Tracy, R., Ribeiro, R. M., Sher, A., Francischetti, I. M. B., Pandrea, I., Sereti, I.
30 Aug 2017 at 1:48pm

In HIV infection, persistent inflammation despite effective antiretroviral therapy is linked to increased risk of noninfectious chronic complications such as cardiovascular and thromboembolic disease. A better understanding of inflammatory and coagulation pathways in HIV infection is needed to optim...


MOF-derived cobalt nanoparticles catalyze a general synthesis of amines
by Jagadeesh, R. V., Murugesan, K., Alshammari, A. S., Neumann, H., Pohl, M.-M., Radnik, J., Beller, M.
21 Sep 2017 at 1:39pm

The development of base metal catalysts for the synthesis of pharmaceutically relevant compounds remains an important goal of chemical research. Here, we report that cobalt nanoparticles encapsulated by a graphitic shell are broadly effective reductive amination catalysts. Their convenient and pract...


The condensin complex is a mechanochemical motor that translocates along DNA
by Terakawa, T., Bisht, S., Eeftens, J. M., Dekker, C., Haering, C. H., Greene, E. C.
7 Sep 2017 at 1:37pm

Condensin plays crucial roles in chromosome organization and compaction, but the mechanistic basis for its functions remains obscure. Here, we use single-molecule imaging to demonstrate that Saccharomyces cerevisiae condensin is a molecular motor capable of ATP hydrolysis-dependent translocation alo...


Single-proton spin detection by diamond magnetometry
by Loretz, M., Rosskopf, T., Boss, J. M., Pezzagna, S., Meijer, J., Degen, C. L.
8 Jan 2015 at 2:55pm

Extending magnetic resonance imaging to the atomic scale has been a long-standing aspiration, driven by the prospect of directly mapping atomic positions in molecules with three-dimensional spatial resolution. We report detection of individual, isolated proton spins by a nitrogen-vacancy (NV) center...


A Single Molecular Spin Valve
by Schon, Emberly, Kirczenow
18 Apr 2002 at 2:53pm

The charge transport through a single benzene-1,4-dithiolate molecule embedded in an inert matrix of insulating alkanethiol molecules and sandwiched between ferromagnetic electrodes is studied as a function of magnetic field. Electronic transport through the device structure shows a pronounced spin ...



British Medical Journal

Risk of relapse after antidepressant discontinuation in anxiety disorders, ob...
25 Sep 2017 at 9:16am
During the editing process of this Research paper (BMJ 2017;358:j3927, doi:10.1136/bmj.j3927) the word ?not? was omitted from the following sentence in the Discussion (third paragraph): ?However, the...

New England Journal of Medicine

Biomarkers and Aging in the News

Mental health staff on long-term stress leave up 22%
The number of staff taking long-term leave has risen steadily over the past five years.
22 Sep 2017 at 12:19am
Using technology to help older adults keep their independence
From a wall that tracks your gait to a stove that buzzes when it's left on, researchers are testing and developing technologies to help keep older adults safer in their own homes.
25 Sep 2017 at 9:57am
This is what happens when gender roles are forced on kids
A new study suggests that across countries and income levels boys and girls enter their teens ingrained with damaging gender stereotypes that could have lasting impacts.
20 Sep 2017 at 7:39pm
Gatorade punished for dissing water in video game
The Gatorade Company will no longer be able to make disparaging comments about water, according to a settlement announced Thursday by California Attorney General Xavier Becerra.
22 Sep 2017 at 5:29pm

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News Analysis: Yes, Aaron Hernandez Suffered Brain Injury. But That May Not E...
The links between biology and behavior are complex, and a number of factors contribute to violence. Yet evidence is mounting that C.T.E. may be involved.
24 Sep 2017 at 5:32pm
An Upbeat Mood May Boost Your Flu Shot?s Effectiveness
Older people who are in a good mood when they get a flu shot have a better immune response.
25 Sep 2017 at 5:36pm
A Stress Link to Lupus
Women exposed to trauma, including serious car crashes or sexual assaults, were at increased risk of developing the autoimmune disorder lupus.
20 Sep 2017 at 12:12pm
The Fatal Toll of Cheap Cigarettes
The availability of cheaper, off-brand cigarettes is associated with an increase in infant mortality.
19 Sep 2017 at 6:00am

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Melanoma cases rising; young women at greatest risk
Study says that could be because they are more likely to use tanning beds than men.        
2 Apr 2012 at 10:15am
Long use of any hormones raises women's breast cancer risk
A new study tracked about 60,000 nurses and found that use of any kind of hormones for 10 years or more slightly raised the chances.        
1 Apr 2012 at 1:28pm
Radiation may up breast cancer risk in some women
Mammograms might raise the chances of developing cancer in young women whose genes put them at higher risk, a study suggests.        
6 Sep 2012 at 6:30pm
U.N.: Chemicals damaging health and environment
The report by the U.N. Environment Program warned that the increasing production of chemicals is increasing health costs.        
6 Sep 2012 at 11:25am
Study: Ginkgo doesn't prevent Alzheimer's disease
Taking ginkgo biloba didn't prevent Alzheimer's disease in older adults, according to the biggest prevention study in Europe.       
5 Sep 2012 at 10:34pm
University pulls Kinsey Institute app over privacy concerns
The Kinsey Institute released a new mobile app that allows users to report on sexual behavior and experiences.       
5 Sep 2012 at 9:43pm
War might be making young bodies old
A VA study finds that veterans in their 20s and 30s show signs of premature aging.       
5 Sep 2012 at 5:56pm

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Express Scripts to limit opioid prescriptions
Move by largest pharmacy benefits manager to lower addiction risks of painkillers draws objections from AMA
16 Aug 2017 at 7:15pm
Why is knee arthritis twice as common as it used to be?
It's estimated that the lifetime risk of developing the condition is 46 percent
15 Aug 2017 at 3:51pm
Why are cases of knee osteoarthritis on the rise?
A new study found osteoarthritis of the knee is more than twice as common as it was just a few generations ago. It's estimated the lifetime risk of developing this condition is 46 percent, but it is possible to protect your knees. Dr. Jordan Metzl, a sports medicine physician at New York's Hospital for Special Surgery, joins "CBS This Morning" to discuss possible reasons for the increase and what you can do to reduce the symptoms.
15 Aug 2017 at 1:13pm
An alcoholic drink per day can lower risk of cardiovascular disease, study says
Having a glass of wine or beer with dinner tonight may be good for you, according to a new study. Researchers found women who had up to one drink a day and men who averaged up to two a day had a lower risk of dying from cardiovascular disease. Dr. Jon LaPook explains.
14 Aug 2017 at 11:45pm
Morning Rounds: Colon cancer deaths, stroke rates among women
Dr. Tara Narula joins "CBS This Morning: Saturday" to discuss a surprising and concerning rise in colon cancer death rates among younger Americans, a new study that shows stroke rates are going down for men but not women and a new development in the on-going battle with antibiotic-resistant bacteria.
12 Aug 2017 at 12:48pm
How to protect your eyes while viewing the solar eclipse
Millions of Americans will look at the sky on Aug. 21 for the first coast-to-coast total eclipse of the sun in 99 years. But if you want to catch a glimpse, you should take precautions to avoid damaging your vision. Ophthamologist Dr. Christopher Starr joins "CBS This Morning" with more on how to protect your eyes.
11 Aug 2017 at 2:39pm
Medigap supplemental coverage can be too pricey for younger Medicare benefici...
One night three years ago, Joe Hobson finished reading a book, went to sleep and woke up blind. The problem, caused by a rare hereditary disease, forced him to give up his 20-year communications job, along with its generous health insurance. Now 63, the Arlington man is covered by Medicare, the f...
7 Mar 2011 at 6:32pm
Type 2 diabetes surges in people younger than 20
U.S. cases in those under 20 have grown from almost zero to tens of thousands in just over a decade.
22 Mar 2011 at 3:48pm
Fear is potent risk of Japanese nuclear crisis
The psychological impact of Japanese nuclear crisis could turn out to be significant
15 Mar 2011 at 5:31am
How men and women exercise differently
No one wants to think she's a cliche. But it's time for me to recognize that when it comes to my gym behavior, that's exactly what I am: a cardio-loving woman who has to be forced to hoist a dumbbell.
1 Mar 2011 at 11:59am
Many Americans have poor health literacy
An elderly woman sent home from the hospital develops a life-threatening infection because she doesn't understand the warning signs listed in the discharge instructions. A man flummoxed by an intake form in a doctor's office reflexively writes "no" to every question because he doesn't understand ...
28 Feb 2011 at 8:37pm
'Policy Review' essay covers PTSD; veteran benefits
How could a Veterans Administration rule making it easier for veterans with post-traumatic stress disorder to file disability claims be a bad thing? In a "Policy Review" essay called "PTSD's Diagnostic Trap," psychiatrist and Yale University School of Medicine lecturer Sally Satel argues that ful...
21 Feb 2011 at 11:47am
Women are more likely than men to give up sleep to care for children and others
Call it the real night shift - that noctural period when bleary-eyed adults leave warm beds to tend to the needs of sick kids, elderly parents, an ailing spouse or incontinent pet. So, who takes the night shift: Mom or Dad?
14 Feb 2011 at 8:22pm
Enrollment in high-risk insurance pools lagging behind predictions
More Americans have been signing up for special health plans designed for people with medical problems that caused them to be spurned by the insurance industry, according to new government figures. But enrollment continues to lag significantly behind original predictions.
10 Feb 2011 at 9:35pm
Why Hard Facts Aren't Enough to Alter Our Beliefs
If we want to affect the behaviors and beliefs of the person in front of us, we need to understand what goes on inside their head.
25 Sep 2017 at 9:24am

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News Analysis: Yes, Aaron Hernandez Suffered Brain Injury. But That May Not E...
The links between biology and behavior are complex, and a number of factors contribute to violence. Yet evidence is mounting that C.T.E. may be involved.
24 Sep 2017 at 5:32pm
An Upbeat Mood May Boost Your Flu Shot?s Effectiveness
Older people who are in a good mood when they get a flu shot have a better immune response.
25 Sep 2017 at 5:36pm
A Stress Link to Lupus
Women exposed to trauma, including serious car crashes or sexual assaults, were at increased risk of developing the autoimmune disorder lupus.
20 Sep 2017 at 12:12pm
The Fatal Toll of Cheap Cigarettes
The availability of cheaper, off-brand cigarettes is associated with an increase in infant mortality.
19 Sep 2017 at 6:00am
The hidden simplicity of subduction megathrust earthquakes

The largest observed earthquakes occur on subduction interfaces and frequently cause widespread damage and loss of life. Understanding the rupture behavior of megathrust events is crucial for earthquake rupture physics, as well as for earthquake early-warning systems. However, the large variability in behavior between individual events seemingly defies a description with a simple unifying model. Here we use three source time function (STF) data sets for subduction zone earthquakes, with moment m...


21 Sep 2017 at 1:47pm
Teaching personal initiative beats traditional training in boosting small bus...

Standard business training programs aim to boost the incomes of the millions of self-employed business owners in developing countries by teaching basic financial and marketing practices, yet the impacts of such programs are mixed. We tested whether a psychology-based personal initiative training approach, which teaches a proactive mindset and focuses on entrepreneurial behaviors, could have more success. A randomized controlled trial in Togo assigned microenterprise owners to a control group (n ...


21 Sep 2017 at 1:47pm
Global mRNA polarization regulates translation efficiency in the intestinal e...

Asymmetric messenger RNA (mRNA) localization facilitates efficient translation in cells such as neurons and fibroblasts. However, the extent and importance of mRNA polarization in epithelial tissues are unclear. Here, we used single-molecule transcript imaging and subcellular transcriptomics to uncover global apical-basal intracellular polarization of mRNA in the mouse intestinal epithelium. The localization of mRNAs did not generally overlap protein localization. Instead, ribosomes were more ab...


21 Sep 2017 at 1:47pm
Liquid phase condensation in cell physiology and disease

Phase transitions are ubiquitous in nonliving matter, and recent discoveries have shown that they also play a key role within living cells. Intracellular liquid-liquid phase separation is thought to drive the formation of condensed liquid-like droplets of protein, RNA, and other biomolecules, which form in the absence of a delimiting membrane. Recent studies have elucidated many aspects of the molecular interactions underlying the formation of these remarkable and ubiquitous droplets and the way...


21 Sep 2017 at 1:47pm
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects ...

Hundreds of circular RNAs (circRNAs) are highly abundant in the mammalian brain, often with conserved expression. Here we show that the circRNA Cdr1as is massively bound by the microRNAs (miRNAs) miR-7 and miR-671 in human and mouse brains. When the Cdr1as locus was removed from the mouse genome, knockout animals displayed impaired sensorimotor gating—a deficit in the ability to filter out unnecessary information—which is associated with neuropsychiatric disorders. Electrophysiologic...


21 Sep 2017 at 1:47pm
Egg Freezing Gives You Options but Has Risks
Doctors say more women are interested in egg freezing, a procedure that may help preserve their fertility but comes with risks.
22 Sep 2017 at 4:51pm
High, Low Magnesium Levels Tied to Dementia Risk
But study didn't prove a cause-and-effect relationship
20 Sep 2017 at 6:15pm
Fracture Risk Higher for Seniors With Diabetes
Bone weaknesses seen in those with blood sugar disease
20 Sep 2017 at 10:15am
Youth Football Increases Odds of Brain Problems
Researchers say greater risk of behavior issues, depression in those who played tackle before age 12
19 Sep 2017 at 4:15pm
One Behavior Best Prevents High Blood Pressure
One critical trait emerged when researchers reviewed smoking and drinking habits, weight, diet and exercise
14 Sep 2017 at 8:19pm
Can Coffee or Tea Extend Survival With Diabetes?
The answer may depend on whether you're a man or a woman
14 Sep 2017 at 2:15pm
Could Artificial Sweeteners Raise Diabetes Risk?
Small study suggests these products might somehow inhibit blood sugar control
14 Sep 2017 at 10:15am

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Health body warns many UK areas have high Lyme disease risk
The South of England and Scottish Highlands have been named as high risk areas for Lyme disease, but infection can occur in many parts of the UK
25 Sep 2017 at 9:20am
Walking to work or doing the vacuuming can extend your life
Just 30 minutes of easy exercise five days a week reduces your risk of premature death by 28 per cent, suggests the world?s largest study of physical activity
21 Sep 2017 at 7:00pm
Old fathers pass on more mutations to kids than old mothers
A huge study of Icelanders suggests that older men pass on four times as many new mutations to their kids than women  
20 Sep 2017 at 2:00pm
Kids everywhere have damaging gender stereotyping set by age 10
Global study reveals that gender stereotypes become ingrained in "tween" years, leading to life-long health consequences - particularly for girls
20 Sep 2017 at 10:00am
Third-hand smoke in furniture and clothes damages mouse organs
Exposure to smoke residue increases rodents? stress hormones and puts them at higher risk of diabetes, as well as harming their livers and brains
14 Sep 2017 at 8:01pm
It?s too easy for bioterrorists to access dangerous research
The systems designed to stop potentially risky research being published and used to make weapons of terror have ?multiple shortcomings?, warns US report
14 Sep 2017 at 12:00pm
Christmas Island?s only echolocating bat has gone extinct
The Christmas Island pipistrelle is no more, and the world's largest antelope is at risk, according to the latest update to the Red List of Threatened Species
14 Sep 2017 at 9:40am
Extreme wildfires in the US could lead to long-term lung damage
This year?s exceptional wildfire season could drag on until December, and the resulting air pollution poses a serious risk to people?s health
12 Sep 2017 at 8:30am
Children's IQ Could Be Lowered By Mothers Drinking Tap Water While Pregnant
Children whose mothers were exposed to high levels of fluoride during pregnancy may be at risk of having a lower IQ.
20 Sep 2017 at 12:30pm
Are Coffee and Tea Healthy? They Could Extend Life for Diabetics, New Study S...
Drinking coffee and tea could extend a diabetic woman's lifespan.
15 Sep 2017 at 5:57pm
Gait Analysis Can Reveal Personality Traits, Walking Speed As You Get Older
Gait analysis reveals your walking speed can reflect your personality traits.
7 Sep 2017 at 6:52pm
Facebook Friends May Get You Sick: Obsessive Social Media Use Triggers URI
A greater number of Facebook friends and social media-induced anxiety/stress can leave you vulnerable to upper respiratory infections.
5 Sep 2017 at 7:11pm

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School Safety Tips For Younger Kids
School is back in session, so take some time to go over these important safety tips with your children. This is just the beginning of the conversation, but it's a great place to get started.
21 Jul 2014 at 8:00am
Egg Freezing Gives You Options but Has Risks
Doctors say more women are interested in egg freezing, a procedure that may help preserve their fertility but comes with risks.
22 Sep 2017 at 4:51pm
High, Low Magnesium Levels Tied to Dementia Risk
But study didn't prove a cause-and-effect relationship
20 Sep 2017 at 6:15pm
Fracture Risk Higher for Seniors With Diabetes
Bone weaknesses seen in those with blood sugar disease
20 Sep 2017 at 10:15am
Youth Football Increases Odds of Brain Problems
Researchers say greater risk of behavior issues, depression in those who played tackle before age 12
19 Sep 2017 at 4:15pm
One Behavior Best Prevents High Blood Pressure
One critical trait emerged when researchers reviewed smoking and drinking habits, weight, diet and exercise
14 Sep 2017 at 8:19pm
Can Coffee or Tea Extend Survival With Diabetes?
The answer may depend on whether you're a man or a woman
14 Sep 2017 at 2:15pm
Could Artificial Sweeteners Raise Diabetes Risk?
Small study suggests these products might somehow inhibit blood sugar control
14 Sep 2017 at 10:15am
Medigap supplemental coverage can be too pricey for younger Medicare benefici...
One night three years ago, Joe Hobson finished reading a book, went to sleep and woke up blind. The problem, caused by a rare hereditary disease, forced him to give up his 20-year communications job, along with its generous health insurance. Now 63, the Arlington man is covered by Medicare, the f...
7 Mar 2011 at 6:32pm
Type 2 diabetes surges in people younger than 20
U.S. cases in those under 20 have grown from almost zero to tens of thousands in just over a decade.
22 Mar 2011 at 3:48pm
Fear is potent risk of Japanese nuclear crisis
The psychological impact of Japanese nuclear crisis could turn out to be significant
15 Mar 2011 at 5:31am
How men and women exercise differently
No one wants to think she's a cliche. But it's time for me to recognize that when it comes to my gym behavior, that's exactly what I am: a cardio-loving woman who has to be forced to hoist a dumbbell.
1 Mar 2011 at 11:59am
Many Americans have poor health literacy
An elderly woman sent home from the hospital develops a life-threatening infection because she doesn't understand the warning signs listed in the discharge instructions. A man flummoxed by an intake form in a doctor's office reflexively writes "no" to every question because he doesn't understand ...
28 Feb 2011 at 8:37pm
'Policy Review' essay covers PTSD; veteran benefits
How could a Veterans Administration rule making it easier for veterans with post-traumatic stress disorder to file disability claims be a bad thing? In a "Policy Review" essay called "PTSD's Diagnostic Trap," psychiatrist and Yale University School of Medicine lecturer Sally Satel argues that ful...
21 Feb 2011 at 11:47am
Women are more likely than men to give up sleep to care for children and others
Call it the real night shift - that noctural period when bleary-eyed adults leave warm beds to tend to the needs of sick kids, elderly parents, an ailing spouse or incontinent pet. So, who takes the night shift: Mom or Dad?
14 Feb 2011 at 8:22pm
Enrollment in high-risk insurance pools lagging behind predictions
More Americans have been signing up for special health plans designed for people with medical problems that caused them to be spurned by the insurance industry, according to new government figures. But enrollment continues to lag significantly behind original predictions.
10 Feb 2011 at 9:35pm

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News Analysis: Yes, Aaron Hernandez Suffered Brain Injury. But That May Not E...
The links between biology and behavior are complex, and a number of factors contribute to violence. Yet evidence is mounting that C.T.E. may be involved.
24 Sep 2017 at 5:32pm
Even for the active, a long sit shortens life and erodes health

Maybe those of us who sit for long hours in meetings, on phone calls, and tapping away at keyboards should be getting hazard pay. New research that distills the findings of 47 studies concludes that those of us who sit for long hours raise our average risk of cancer, cardiovascular disease, type...


19 Jan 2015 at 5:09pm
West Nile virus has killed 8 Californians this year. In parts of L.A. County,...

Julie Shepherd ended up in the hospital earlier this month after her neighbor found her on the floor of her West Covina home, unable to move.

Shepherd, 84, was paralyzed and had lost the ability to speak. Doctors diagnosed her illness as West Nile virus.

Humans contract the virus through a mosquito...


23 Sep 2017 at 8:00am
Domestic violence homicide rate drops with stricter gun law, study finds

When domestic violence offenders are required to relinquish their guns, instead of simply being barred from owning firearms, the risk that those offenders may kill their partners goes down, a new study finds.

The paper, described in the Annals of Internal Medicine, highlights a simple method for...


19 Sep 2017 at 5:20pm
Up to 7 years of hormone therapy is safe for postmenopausal women, new data show

For decades now, women navigating menopause have been buffeted by shifting research findings on the risks and possible benefits of hormone-replacement therapy. Now, a landmark clinical trial that followed more than 27,000 subjects for roughly 18 years has offered some conclusive evidence that neither...


12 Sep 2017 at 7:20pm
Get up at least once every 30 minutes. Failure to do so may shorten your life...

You can spend a lot of accumulated time on your bottom in the course of a day. Or you can sit for lengthy spells without a break.

Both, it turns out, are very bad for you.

Whether you?re a heavy sitter or a binge-sitter, racking up prolonged sedentary time increases your risk of early death, according...


11 Sep 2017 at 7:50pm

NIH Press Releases



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NIH News Release
NIH News Release
News releases from the National Institutes of Health (NIH)

Affective neuroscience expert Dr. Richard Davidson to speak on meditation res...
20 Apr 2016 at 1:00pm
NCCIH presents ?Change Your Brain by Transforming Your Mind?.


NIH study finds factors that may influence influenza vaccine effectiveness
19 Apr 2016 at 8:30pm
Long-held approach to predicting seasonal influenza vaccine effectiveness may need to be revisited.


Statement on Review of NIH Sterile Production Facilities
19 Apr 2016 at 8:15pm
Production suspended in two facilities.


NCI opens online platform to submit ideas about research for Cancer Moonshot
18 Apr 2016 at 8:15pm
Submissions will be considered by a panel of scientific experts and patient advocates.


Healthy diet may reduce high blood pressure risk after gestational diabetes, ...
18 Apr 2016 at 8:00pm
Women who have had gestational diabetes may indeed benefit from a diet rich in fruits, vegetables, and whole grains.


NIH launches research program to reduce health disparities in surgical outcomes
18 Apr 2016 at 3:00pm
The initiative will involve collaborations among several NIH institutes and centers, AHRQ.


Islet transplantation restores blood sugar awareness and control in type 1 di...
18 Apr 2016 at 2:00pm
NIH-funded study lays groundwork for potential application submission to FDA for licensure of islet preparation.


Greenness around homes linked to lower mortality
15 Apr 2016 at 4:00pm
Researchers found the biggest differences in death rates from kidney disease, respiratory disease, and cancer.


NIH sequences genome of a fungus that causes life-threatening pneumonia
11 Apr 2016 at 3:00pm
Pneumocystis was one of the first infections that led to the initial recognition of the HIV/AIDS epidemic.


New role identified for scars at the site of injured spinal cord
7 Apr 2016 at 7:00pm
NIH-funded mouse study suggests scar formation may help, not hinder, nerve regrowth.


NIH Announcements


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NIH Funding Opportunities (Notices, PA, RFA)
Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.

Notice of Intent to Publish a Funding Opportunity Announcement for Conformanc...
12 Dec 2016 at 11:52am
Notice NOT-FD-17-001 from the NIH Guide for Grants and Contracts
Reminder: NHLBI FY2017 Small Business Topics of Special Interest (TOSI) for t...
12 Dec 2016 at 11:48am
Notice NOT-HL-16-479 from the NIH Guide for Grants and Contracts
Notice of Extension of the Expiration Date for PA-16-282 Developing New Clini...
12 Dec 2016 at 1:25am
Notice NOT-HS-17-005 from the NIH Guide for Grants and Contracts
Notice of an Informational Webinar for RFA-NS-17-017 "Frontotemporal Degenera...
12 Dec 2016 at 3:09am
Notice NOT-NS-17-010 from the NIH Guide for Grants and Contracts
NIH-DoD-VA Pain Management Collaboratory - Pragmatic Clinical Trials Demonstr...
12 Dec 2016 at 3:33am
Funding Opportunity RFA-AT-17-001 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit UG3/UH3 phased cooperative agreement research applications to conduct efficient, large-scale pragmatic clinical trial Demonstration Projects within the NIH-DoD-VA Pain Management Collaboratory on non-pharmacological approaches to pain management and other co-morbid conditions in U.S. military personnel, veterans and their families. This program will be referred to as the NIH-DoD-VA Pain Management Collaboratory program. Awards made under this FOA will initially support a two-year milestone-driven planning phase (UG3), with possible transition to a pragmatic trial Demonstration Project implementation phase (UH3). UG3 projects that have met the scientific milestone and feasibility requirements may transition to the UH3 phase. The UG3/UH3 application must be submitted as a single application, following the instructions described in this FOA. The overall goal of this initiative, jointly supported by the NIH, DoD, and VA, is to develop the capacity to implement cost-effective large-scale clinical research in military and veteran health care delivery organizations focusing on non-pharmacological approaches to pain management and other comorbid conditions. The NIH, DoD, and VA expect to: establish a Coordinating Center that will provide national leadership and technical expertise for all aspects of health care system (HCS_- focused research including assistance to UG3/UH3 grant applicants. Primary outcomes of treatment interventions include assessing pain and pain reduction, ability to function in daily life, quality of life, and medication usage/reduction/discontinuation. Secondary outcomes focusing on assessing comorbid conditions or those co-occurring with high frequency in this population are also of interest under the FOA.
NIH-DoD-VA Pain Management Collaboratory - Coordinating Center (U24)
12 Dec 2016 at 3:33am
Funding Opportunity RFA-AT-17-002 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications for a Coordinating Center (CC) to provide national leadership for the NIH-DoD-VA Health Care Systems (HCS) Research Collaboratory program on non-pharmacological approaches to pain management and comorbidities in U.S. military personnel, veterans and their families. For brevity, this initiative will be referred to as the NIH-DoD-VA Pain Management Collaboratory. Coordinating Center applicants will need to: 1) develop, adapt, and adopt technical and policy guidelines and best practices for the effective conduct of research in partnership with health care systems focused on military personnel, veterans, and their families; 2) work collaboratively with and provide technical, design, and other support to Demonstration Project teams, to develop and implement a pragmatic trial protocol; and 3) disseminate widely Collaboratory-endorsed policies and best practices and lessons learned in the Demonstration Projects for implementing research within health care settings. The Coordinating Center will also serve as the central resource for the activities of the NIH-DoD-VA Pain Management Collaboratory program, including providing administrative support for a Steering Committee and its subcommittees.
Innovations for Healthy Living - Improving Population Health and Eliminating ...
12 Dec 2016 at 12:04pm
Funding Opportunity RFA-MD-17-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) grant applications that propose to develop a product, process or service for commercialization with the aim of reducing disparities in healthcare access and health outcomes and in preventing disease and improving health in one or more NIH-defined health disparity population group(s). Appropriate technologies should be effective, affordable, culturally acceptable, and deliverable to racial/ethnic minorities, low-income and rural populations.
Technologies for Improving Minority Health and Eliminating Health Disparities...
12 Dec 2016 at 12:04pm
Funding Opportunity RFA-MD-17-002 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) grant applications that propose to develop a product, process or service for commercialization with the aim of reducing disparities in healthcare access and health outcomes in one or more NIH-defined health disparity population group(s). Appropriate technologies should be effective, affordable, culturally acceptable, and deliverable to racial/ethnic minorities, low-income and rural populations.
Novel Analytical Approaches for Metabolomics Data (R03)
12 Dec 2016 at 9:57am
Funding Opportunity RFA-RM-17-001 from the NIH Guide for Grants and Contracts. The purpose of this small research grant Funding Opportunity Announcement (FOA) is to foster collaboration between computational scientists, metabolomics experts, and biomedical researchers in developing, piloting, and/or validating novel bioinformatic approaches that address current analytical hurdles in metabolomics data. A goal of providing powerful approaches that will be useful to biomedical researchers, as well as bioinformaticians, is particularly encouraged. Projects are not intended to supplement ongoing metabolomics analyses, but to provide a tool for broader use by the biomedical research community. Projects are expected to use existing, publicly available metabolomics data and complement the efforts and resources of the Common Fund Metabolomics Program.
Utilizing Health Information Technology to Scale and Spread Successful Practi...
12 Dec 2016 at 10:39am
Funding Opportunity PA-17-077 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites R18 grant applications for research that demonstrates how health information technology (IT) can improve patient-centered health outcomes and quality of care in primary care and other ambulatory settings through the scale and spread of successful, health IT-enabled practice models that use patient-reported outcome (PRO) measures to achieve these objectives.
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp)
12 Dec 2016 at 1:27am
Funding Opportunity PA-17-078 from the NIH Guide for Grants and Contracts. The Office of Research on Women's Health (ORWH) announces the availability of administrative supplements to support research highlighting the impact of sex/gender influences and/or sex and gender factors in human health and illness, including basic, preclinical, clinical and behavioral studies. Of special interest are studies relevant to understanding the significance of biological sex on cells and tissue explants; comparative studies of male and female tissues, organ systems and physiological systems; sex-based comparisons of pathophysiology, biomarkers, gene expression, clinical presentation and prevention and treatment of diseases. The most robust experimental designs include consideration of both sex and gender; therefore, applications proposing to investigate the influence of both sex and gender factors are highly encouraged. The proposed research must address at least one objective from Goals 1 through 3 of the NIH Strategic Plan for Women's Health Research.
Shared Instrumentation Grant (SIG) Program (S10)
12 Dec 2016 at 10:19am
Funding Opportunity PAR-17-074 from the NIH Guide for Grants and Contracts. The Shared Instrument Grant (SIG) Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $50,000. There is no maximum price requirement; however, the maximum award is $600,000. Types of instruments supported include, but are not limited to: X-ray diffractometers, mass and nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, cell sorters, and biomedical imagers.
Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10)
12 Dec 2016 at 11:23am
Funding Opportunity PAR-17-075 from the NIH Guide for Grants and Contracts. The Shared Instrumentation for Animal Research (SIFAR) Grant Program encourages applications from groups of NIH-funded investigators to purchase or upgrade scientific instruments necessary to carry out animal experiments in all areas of biomedical research supported by the NIH. Applicants may request clusters of commercially available instruments configured as specialized integrated systems or as series of instruments to support a thematic workflow in a well-defined area of research using animals or related materials. Priority will be given to specialized clusters of instruments and to uniquely configured systems to support innovative and potentially transformative investigations. Requests for a single instrument will be considered only if the instrument is to be placed in a barrier facility. This Funding Opportunity Announcement (FOA) supports requests for state-of-the art commercially available technologies needed for NIH-funded research using any vertebrate and invertebrate animal species. It is expected that the use of the awarded instruments will enhance the scientific rigor of animal research and improve the reproducibility of experimental outcomes. One item of the requested instrumentation must cost at least $50,000. No instrument in a cluster can cost less than $20,000. There is no maximum price requirement; however, the maximum award is $750,000.
High-End Instrumentation (HEI) Grant Program (S10)
12 Dec 2016 at 12:15pm
Funding Opportunity PAR-17-076 from the NIH Guide for Grants and Contracts. The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $600,001. The maximum award is $2,000,000. Types of instruments supported include, but are not limited to: X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-sorters, and biomedical imagers.
Increasing the Use of Medications for the Treatment of Alcohol Use Disorders ...
12 Dec 2016 at 3:26am
Funding Opportunity PAR-17-079 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages health services research designed to increase the public health impact of Food and Drug Administration (FDA)-approved pharmacotherapies for the treatment of alcohol use disorder. Significant progress is needed in developing generalizable, scalable, cost-effective strategies to move these evidence-based interventions into the mainstream of alcohol use disorder treatment, in both general medical and specialty care settings. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) seeks applications to conduct hypothesis-driven research to identify effective methods for increasing the utilization of currently-available medications, by addressing their acceptability (to prescribers and patients), perceived effectiveness, affordability, and feasibility of use within existing care delivery systems.